BOOK Hotels IN Defiance, USA

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Defiance - 9 Hotels to Choose From

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Holiday Inn Express Hotel & Suites Defiance, an IHG Hotel

1148 Hotel Drive, Defiance, USA - See map

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Hampton Inn Defiance

1037 Hotel Dr, Defiance, USA - See map

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Quality Inn

1068 Hotel Dr, Defiance, USA - See map

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Super 8 by Wyndham Defiance

1053 Hotel Dr. US Hwy 24 & SR 66, Defiance, USA - See map

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Hillside Cabin on 43 Acres w/ Private Lake & View!

150 Homestead Ridge Drive, Defiance, USA - See map

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The Ruebling House Cozy 2nd-floor Apartment!

2987 S Missouri 94, Defiance, USA - See map

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The Reubling House - Modern-rustic Cabin!

2987 S Missouri 94, Defiance, USA - See map

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'the Ruebling House' Historic Defiance Apartment!

2987 S Missouri 94, Defiance, USA - See map

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'the Ruebling House': Bright, Modern, & Renovated!

2987 S Highway 94, Defiance, USA - See map

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Top Picks for Hotels in Defiance

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The Ruebling House Cozy 2nd-floor Apartment!

Defiance, US

With a stay at this apartment in Defiance, you'll be steps from Yellow Farmhouse Winery and a 3-minute drive from Sugar Creek Winery. This apartment is 30.2 mi (48.7 km) from Six Flags St. Louis and 1.5 mi (2.4 km) from Chandler Hill Vineyards. Make yourself comfortable in this apartment, featuring a kitchen with a refrigerator and an oven. Complimentary wireless Internet access is available to keep you connected. Conveniences include a microwave and a ceiling fan. Free self parking is available onsite.

'the Ruebling House' Historic Defiance Apartment!

Defiance, US

'the Ruebling House': Bright, Modern, & Renovated!

Defiance, US

With a stay at this apartment in Defiance, you'll be steps from Yellow Farmhouse Winery and a 3-minute drive from Sugar Creek Winery. This apartment is 30.2 mi (48.7 km) from Six Flags St. Louis and 1.5 mi (2.4 km) from Chandler Hill Vineyards. Make yourself comfortable in this air-conditioned apartment, featuring a kitchen with a refrigerator and an oven. Complimentary wireless Internet access is available to keep you connected. Conveniences include a microwave and a ceiling fan. Free self parking is available onsite.

Hillside Cabin on 43 Acres w/ Private Lake & View!

Defiance, US

With a stay at this cottage in Defiance, you'll be within a 5-minute drive of Chandler Hill Vineyards and Historic Daniel Boone Home and Heritage Center. This cottage is 32.2 mi (51.8 km) from Six Flags St. Louis and 3.9 mi (6.3 km) from Matson Hill Park Trailhead. Make yourself comfortable in this air-conditioned cottage, which features a fireplace. There's a private patio. A kitchen is outfitted with a refrigerator, an oven, and a stovetop. Conveniences include a microwave and a ceiling fan. null

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Quality Inn

A stay at Quality Inn places you in the heart of Defiance, a 4-minute drive from ProMedica Defiance Regional Hospital and 5 minutes from Mercy Health - Defiance Hospital. This hotel is 4.8 mi (7.8 km) from Independence Dam State Park and 17.3 mi (27.9 km) from Henry County Hospital. Make yourself at home in one of the 61 guestrooms featuring refrigerators and microwaves. Flat-screen televisions with cable programming provide entertainment, while complimentary wireless Internet access keeps you connected. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and coffee/tea makers, as well as phones with free local calls. Featured amenities include complimentary newspapers in the lobby, a 24-hour front desk, and luggage storage. Free self parking is available onsite.

Holiday Inn Express Hotel & Suites Defiance, an IHG Hotel

Located in Defiance, Holiday Inn Express Hotel & Suites Defiance, an IHG Hotel is in a rural location, a 4-minute drive from ProMedica Defiance Regional Hospital and 6 minutes from Mercy Health - Defiance Hospital. This hotel is 4.9 mi (7.9 km) from Independence Dam State Park and 17.4 mi (28 km) from Henry County Hospital. Make yourself at home in one of the 62 air-conditioned rooms featuring refrigerators and flat-screen televisions. Complimentary wireless Internet access keeps you connected, and satellite programming is available for your entertainment. Private bathrooms have complimentary toiletries and hair dryers. Conveniences include safes and desks, as well as phones with free local calls. Featured amenities include a business center, express check-in, and express check-out. Event facilities at this hotel consist of conference space and a meeting room. Free self parking is available onsite.

Hampton Inn Defiance

A stay at Hampton Inn Defiance places you in the heart of Defiance, a 4-minute drive from ProMedica Defiance Regional Hospital and 6 minutes from Mercy Health - Defiance Hospital. This spa hotel is 4.9 mi (8 km) from Independence Dam State Park and 17.4 mi (28.1 km) from Henry County Hospital. Make yourself at home in one of the 76 air-conditioned rooms featuring refrigerators and microwaves. Complimentary wired and wireless Internet access keeps you connected, and cable programming provides entertainment. Bathrooms have bathtubs or showers and hair dryers. Conveniences include safes and complimentary newspapers, as well as phones with free local calls. Featured amenities include complimentary wired Internet access, a business center, and express check-in. Free self parking is available onsite.

Super 8 by Wyndham Defiance

Defiance, US

Good

135 Guest reviews

Located in Defiance, Super 8 by Wyndham Defiance is a 4-minute drive from ProMedica Defiance Regional Hospital and 6 minutes from Mercy Health - Defiance Hospital. This hotel is 5 mi (8 km) from Independence Dam State Park and 17.4 mi (28 km) from Henry County Hospital. Make yourself at home in one of the 50 air-conditioned rooms featuring refrigerators and microwaves. LED televisions are provided for your entertainment. Bathrooms have bathtubs or showers and hair dryers. Conveniences include desks and coffee/tea makers, and housekeeping is provided daily. Featured amenities include a 24-hour front desk, laundry facilities, and a vending machine. Free self parking is available onsite.

The Reubling House - Modern-rustic Cabin!

Defiance, US

With a stay at this cottage in Defiance, you'll be steps from Yellow Farmhouse Winery and a 3-minute drive from Sugar Creek Winery. This cottage is 30.2 mi (48.7 km) from Six Flags St. Louis and 1.5 mi (2.4 km) from Chandler Hill Vineyards. Make yourself comfortable in this air-conditioned cottage, featuring a kitchen with a refrigerator and an oven. Complimentary wireless Internet access is available to keep you connected. Conveniences include a microwave and a ceiling fan. Free self parking is available onsite.

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FAQs About Hotels in Defiance

What's the best place to stay in Defiance, Missouri, USA?

The Inn at Defiance is highly recommended for its excellent location, comfortable rooms, and friendly staff.

What's the best place to stay on a budget in Defiance, Missouri, USA?

The Econo Lodge Defiance offers affordable accommodations without compromising on quality, making it a great option for budget-conscious travelers.

What are some family-friendly hotels in Defiance, Missouri, USA?

The Holiday Inn Express Defiance and Comfort Inn Defiance are both renowned for their family-friendly amenities and services.

What's the best accommodation for a romantic getaway to Defiance, Missouri, USA?

The Defiance Ridge Vineyards offers a romantic atmosphere with its scenic views, luxury accommodations, and wine tasting experiences.

What's the best accommodation for an all-inclusive stay in Defiance, Missouri, USA?

Currently, there are no all-inclusive accommodations in Defiance, Missouri. However, many hotels offer inclusive amenities and packages.

Where can I find pet-friendly hotels in Defiance, Missouri, USA?

The Holiday Inn Express Defiance and Econo Lodge Defiance both welcome pets, ensuring a comfortable stay for your furry friends.

What's the best boutique hotel in Defiance, Missouri, USA?

The Inn at Defiance stands out as the top boutique hotel in Defiance with its charming decor, personalized service, and unique ambiance.

What's the best spa hotel in Defiance, Missouri, USA?

While Defiance doesn't have dedicated spa hotels, the Inn at Defiance offers spa services for guests, ensuring a relaxing stay.

What hotels in Defiance, Missouri, USA have nice views?

Defiance Ridge Vineyards and the Inn at Defiance boast breathtaking views of the surrounding countryside, creating a picturesque setting for your stay.

Do hotels in Defiance, Missouri, USA offer airport transportation services?

Most hotels in Defiance, Missouri do not provide airport transportation services. However, it's recommended to check with individual hotels for any available options.

Destination

Discovering Defiance's Coastal Charm and Urban Wonders

Discover what to do and what to see in Defiance

Defiance, Missouri, USA Welcome to the charming town of Defiance, Missouri, where history meets natural beauty. Nestled in the heart of wine country, this picturesque destination is perfect for a relaxing getaway. Immerse yourself in the rich history of the town as you explore its landmarks. Discover the Daniel Boone Home, the former residence of the famous American pioneer. Take a step back in time as you walk through the restored rooms and learn about the life and adventures of Daniel Boone. For nature enthusiasts, Defiance offers an abundance of outdoor experiences. Hike the scenic trails at Klondike Park, where you'll be rewarded with breathtaking views of the Missouri River Valley. Enjoy a leisurely bike ride along the Katy Trail, which winds through forests and scenic landscapes. After a day of exploration, retreat to your cozy accommodation at Travala.com. Our hotel in Defiance provides comfortable rooms with modern amenities. Each room is designed to ensure a peaceful and restful night's sleep. To make your booking experience convenient, Travala.com offers multiple payment options. Choose to pay with credit cards, debit cards, or even cryptocurrencies like Bitcoin. We believe in providing our guests with flexibility and hassle-free transactions. Whether you're seeking a romantic escape or a family adventure, Defiance, Missouri has something for everyone. Immerse yourself in the beauty of the town, explore its rich history, and indulge in the local wine culture. Book your stay at Travala.com in Defiance and create unforgettable memories.